ABSTRACT
Lipoblastoma is a rare benign mesenchymal tumor that exhibits a tendency to invade locally but not to metastasize, and develops from embryonic remnants of white fat tissue. We experienced a case of lipoblastoma occurring in a 7-month-old girl. A small nodule developed on her right inguinal region at the age of 4 months. It had grown to be a 1.2x2.0cm in size, well-defined, volcano-like, ovoid erythematous nodule. Histopathologically it was composed of well-defined lobulated fat tissue with multivacuolated lipoblasts, undifferentiated mesenchymal cells such as stellate or spindle cells and minimal myxoid stroma. Electron microscopic findings demonstrated lipoblasts with eccentric nuclei and coarse chromatins. Complete local excision was done.
Subject(s)
Female , Humans , Infant , Adipose Tissue, White , Chromatin , LipoblastomaABSTRACT
BACKGROUND: Despite concern about prevention of dermatophytosis, little is known about the survival period of dermatophytes. OBJECTIVE: The purpose of the study was to investigate the survival period of dermatophytes according to various environmental conditions. METHODS: Scales for testing were collected from skin lesions of 25 patients with dermatophytosis. They were categorised into different treatment groups: kept scales themselves(S), scales in a humid condition(S+H), scales mixed with sterilized dusts(S+D), and scales mixed with sterilized dusts in a humid condition(S+D+H). They were then cultured on Sabouraud dextrose agar once a week until there was no colony growth. Data was evaluated with the Mann-Whitney U-test. RESULTS: 1) The mean survival period of Microsporum canis isolated from 5 patients with tinea(T.) capitis was 17.6(S+D+H), 16.6(S+D), 8.4(S+H) and 7 weeks(S). 2) The mean survival period of Trichophyton rubrum isolated from 20 patients of T. corporis, T. cruris, T. pedis & T. unguium was 11.8, 7.4, 9.4 and 12.2 weeks(S+D+H); 7.4, 6.8, 9.2 and 7.4 weeks(S+D); 6.6, 3.4, 8.0 and 10.4 weeks(S+H); 5.0, 2.8, 5.4, 8.2 weeks(S), respectively. CONCLUSION: We found that the survival period of dermatophytes was longest in scales mixed with sterilized dusts in a humid condition.
Subject(s)
Humans , Agar , Arthrodermataceae , Dust , Glucose , Microsporum , Skin , Tinea , Trichophyton , Weights and MeasuresABSTRACT
We report a case of an erythrodermic form of mycosis fungoides in a 68-year-old male, who showed generalized erythroderma with scales for 3 months. Lymphadenopathies in the inguinal and neck areas were present. Histopathological findings showed epidermotropism, perivascular atypical lymphocyte infilteration in the upper dermis, and dermatopathic lymphadenopathy in the inguinal lymph node. T cell markers were positively stained in the immunohistochemical study. These clinicopathological features were consistent with an erythrodermic form of mycosis fungoides(TNM IIl). The patient was treated with PUVA therapy and low dose chemotherapy.
Subject(s)
Aged , Humans , Male , Dermatitis, Exfoliative , Dermis , Drug Therapy , Lymph Nodes , Lymphatic Diseases , Lymphocytes , Mycosis Fungoides , Neck , PUVA Therapy , Weights and MeasuresABSTRACT
Papillary eccrine adenoma, first described by Rulon and Helwig in 1977, is a rare benign adnexal neoplastn. It is usually present as a solitary dermal nodule on the distal extremities. It has characteristic histopathological findings, consisting of dilated ducts that contain eosinophilic secretions and are associated with intralummal papillations. On the basis of histological and histochemical studies it is believed to be an adnexal neoplasm of possible eccrine differentiation. We report two recent cases of papillary eccrine adenomas occuring in two young male patients without subjective symptoms who had firm dermal nodules on the extremities.
Subject(s)
Humans , Male , Adenoma , Eosinophils , ExtremitiesABSTRACT
BACKGROUND: Clinical concern and incidence of mycotic keratitis in ophthalmic practice has been increasing. OBJECTIVE: The purpose of this study was to investigate clinical and mycological feature of mycotic keratitis. METHODS: We evaluated the clinical and mycological aspect of mycotic keratitis in 14 patients from October 1993 to March 1997 in Dongguk Unversity Hospital. RESULTS AND CONCLUSION: Mycotic keratitis showed high incidence in fifth (42.9%), sixth (35.7%), and fourth decade (14.3%). The ratio of male to female patient was 1:3.6. The seasonal prevalence was highest in autumn. A scratch or abrasion from vegetation was the most common type of the eye trauma in mycotic keratitis. The positive rate of KOH examination and culture was 92.9%, respectively. The common causative organisms of mycotic keratitis were Fusarium sp. (38.5%) and Alternaria sp. (38.5%), followed by Curvularia sp. (7.7%), Aspergillus flavus (7.7%) and Acremonium sp. (7.7%).
Subject(s)
Female , Humans , Male , Acremonium , Alternaria , Aspergillus flavus , Fusarium , Incidence , Keratitis , Prevalence , SeasonsABSTRACT
We report two cases of cutaneous Mycobacterium(M.) marinum infections in a 43-year-old man and a 31-year-old woman who had multiple subcutaneous nodules on the left upper extremity and an erythematous ulcer on the right elbow, respectively. Skin biopsy specimens revealed chronic granulamatous inflammation and AFB positive bacilli in the dermis. The culture from tissue specimens on Lowenstein-Jensen media at 30'C for 10 days, yielded cream-colored colonies, which became yellow when exposed to light. The organism was identified as M. marinum by selected biochemical reactions. The patients were treated with surgical excision followed by administration of minocycline and administration of minocycline, respectively.
Subject(s)
Adult , Female , Humans , Biopsy , Dermis , Elbow , Inflammation , Minocycline , Mycobacterium marinum , Mycobacterium , Skin , Ulcer , Upper ExtremityABSTRACT
We report a case of vulvar syringoma suggesting milia. A 20-year-old pregnant woman visited the obstetrical department of our hospital for labor pain. On physical examination, the skin lesions were revealed accidently and showed symmetrically distributed, numerous, 2-4mm sized, yellow to skin colored papules on the vulva. The lesions developed in the fifth gestational month and were aggravated thereafter. After delivery, we performed a skin biopsy of the lesion. Histopathologic findings of the biopsy specimen showed the typical findings of syringoma and milia.
Subject(s)
Female , Humans , Pregnancy , Young Adult , Biopsy , Labor Pain , Physical Examination , Pregnant Women , Skin , Skin Pigmentation , Syringoma , VulvaABSTRACT
We report a case of chromoblastomycosis caused by Fonsecaea(F.) pedrosoi in a 58-year-old female, who showed a 2 x1.5cm sized, scply erythematous plaque on the left wrist for 7 months. Histopathologically, chronic granulomatous inflammation and sclerotic cells were observed. Fungal culture grew out th typical black colonies of F. pedrosoi. The patient had been treated with weekly intralesional injections of amphotericin B for 3 months. We observed a good response without evidence of recurrence.
Subject(s)
Female , Humans , Middle Aged , Amphotericin B , Chromoblastomycosis , Inflammation , Injections, Intralesional , Recurrence , WristABSTRACT
Meralgia paresthetica is a syndrome consisting of numbness, pain, tingling, burning and/or a variety of other paresthesias on the distribution of the lateral femoral cutaneous nerve (LFCN) of the thigh. We report a case of meralgia paresthetica in a 41-year-old woman who complained of the symptoms of pain, burning sensation, and dysesthesia which occurred whilst standing up without any other constitutional symptoms. The authors suspect that frequent. and persistent squatting may play a role in the development of the present symptoms.
Subject(s)
Adult , Female , Humans , Burns , Hypesthesia , Paresthesia , Sensation , ThighABSTRACT
No abstract available.
ABSTRACT
Hyperkeratosis of the nipple and areola is a rare condition. We report a case of hyperkeratosis of the nipple and areola occurrinp in man with no underlying endocrirop thy or synthetic estrogenic drug therapy. The patient was not associated with epidermal nevus orichthyosis and so fitted into the nevoid form of hyperkeratosis of the nipple and areola. The clinical appearance and histological findings of the lesion were the same as those reported before. He showed a slight improvement in the color and hyperkeratcsis of the nipple and areola with 6 months use of a topical keratolytic agent and corticosteroid crearn.